As a part of the Porta Romana, the CityLine Hotel Liberty offers a central location. Guests can walk to the Navigli and the Bocconi University, and the Brera Pinoteca Art Gallery is just a bit farther along. It is 7 kilometers to the Milan Central Station from the CityLine Hotel Liberty, though this journey can be accomplished via the nearby underground station.

There are 58 rooms in total, decorated in a modern Italian style with colored glass in the windows. Rooms are available in a number of classes, including suites. Rooms have cable television service, Internet connections, hydro massage showers, and mini bars.

Catering to business and leisure travelers, the property offers a fully air conditioned and modern interior. The lobby area and the garden provide relaxation space, and there is a private room for meetings or social events for up to 20 people. The bar has leather armchairs and a television in the lounge area for sports. A buffet breakfast is offered for a fee in the mornings. The hotel has its own private garage for guests.